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Heparin Derivatives
Heparin is a complex polysaccharide composed of repeating disaccharides of uronic acid -> glucosamine.   The disaccharide units may be biosynthetically modified as N-acetyl or N-sulfate glucosamine, 2-O-sulfate uronic acid and 6-O-sulfate and/or 3-O-sulfate glucosamine.   Heparin Derivatives consist of a group of products derived from heparin, made by one or more chemical modifications.   The modifications are designed to change the activity of relevant groups of the molecules, thus to provide a wide range of heparin derivatives for structure-function study and biological activity analysis.

Over Sulfated Heparin
 Catalog No. GT6020: Size = 2 mg/vial; Price = $138.00
Over Sulfated Heparin is a derivative in which all primary hydroxyls in glucosamine residues and a large proportion of secondary hydroxyl groups in disaccharide units have been substituted by O-sulfate esters.

Carboxyl-Reduced Heparin
 Catalog No. GT6060: Size = 2 mg/vial; Price = $85.00
Carboxyl-Reduced Heparin is a derivative in which the carboxyl group of uronic acid residues of heparin have been reduced to alcohols.   The disaccharide units in the derivative are either glucose -> glucosamine or idose -> glucosamine.

Periodate-Oxidized Heparin
 Catalog No. GT6070: Size = 2 mg/vial; Price = $125.00
Periodate-Oxidized Heparin is a derivative in which all unsulfated uronic acid residues of heparin are oxidized by periodic acid.   After periodate oxidation the newly formed aldehydes are reduced to primary alcohols.

Fully De-O-Sulfated Heparin
 Catalog No. GT6011: Size = 2 mg/vial; Price = $115.00
De-O-Sulfated Heparin is a derivative in which all O-sulfate esters of heparin have been removed without changing the backbone structure.   Most of the negative charge contributed by O-sulfates has been eliminated.

2-O-Desulfated Heparin
 Catalog No. GT6012: Size = 2 mg/vial; Price = $95.00
2-O-Desulfated Heparin is a derivative in which only the O-sulfate groups on C-2 of uronic acid residues have been removed.   The backbone structure of the derivative is unchanged but all uronic acid residues become unsubstituted.

6-O-Desulfated Heparin
 Catalog No. GT6013: Size = 2 mg/vial; Price = $155.00
6-O-Desulfated Heparin is a derivative in which most of O-sulfate groups on C-6 of glucosamine residues have been removed while most of the 2-O-sulfate / 3-O-sulfate groups are remain intact.

Fully N-Acetylated Heparin
 Catalog No. GT6031: Size = 2 mg/vial; Price = $168.00
Fully N-Acetylated Heparin is a heparin derivative prepared by N-acetylation of De-N-Sulfated Heparin.   All disaccharide units in the derivative are uronic acid -> N-acetyl-glucosamine units.

Fully N-Sulfated Heparin
 Catalog No. GT6041: Size = 2 mg/vial; Price = $158.00
Fully N-Sulfated Heparin is a derivative made by N-sulfation of De-N-Acetylated Heparin.   The sequence of the disaccharide units in the derivative are exclusively uronic acid -> N-sulfate-glucosamine.

De-N-Sulfated Heparin
 Catalog No. GT6030: Size = 2 mg/vial; Price = $105.00
De-N-Sulfated Heparin is a derivative in which N-sulfate groups of the N-sulfated-glucosamine residues of heparin are removed.   The altered disaccharide residues in the derivative become uronic acid -> glucosamine, while the unmodified disaccharide units remain as uronic acid -> N - acetyl-glucosamine.

De-N-Acetylated Heparin
 Catalog No. GT6040: Size = 2 mg/vial; Price = $95.00
De-N-Acetylated Heparin is a heparin derivative in which all N-acetyl groups of the N-acetyl-glucosamine residues of heparin have been depleted.   The altered disaccharide unit in the derivative becomes uronic acid -> glucosamine while the unmodified disaccharide unit remains as uronic acid -> N-sulfate-glucosamine.

Heparin Derived Oligosaccharides
Heparin Derived Oligosaccharide is a group of compounds made from heparin by controlled deaminative cleavage and subsequent purification according to the degree of polymerization.   Each oligosaccharide has a specific disaccharide unit of uronic acid -> anhydromannitol at the reducing end and various numbers of disaccharide units at the non-reducing end, depending on the size of the oligosaccharide.

Disaccharide, MW 600 Da
 Catalog No. GT8011: Size = 2 mg/vial; Price = $285.00

Tetrasaccharide, MW 1200 Da
 Catalog No. GT8021: Size = 2 mg/vial; Price = $285.00

Hexasaccharide, MW 1800 Da
 Catalog No. GT8031: Size = 2 mg/vial; Price = $285.00

Octasaccharide, MW 2400 Da
 Catalog No. GT8041: Size = 2 mg/vial; Price = $285.00

Decasaccharide, MW 3000 Da
 Catalog No. GT8051: Size = 2 mg/vial; Price = $285.00

Heparin Oligosaccharide I, MW ~3500 Da
 Catalog No. GT8071: Size = 2 mg/vial; Price = $325.00

Heparin Oligosaccharide II, MW~ 4200 Da
 Catalog No. GT8081: Size = 2 mg/vial; Price = $325.00

Heparin Derived Polysaccharide
Heparin Derived Polysaccharide is a group of compounds made by chromatographic fractionation of heparin.   The molecular weight of each compound is determined by size-exclusive HPLC using molecular weight standards.

Heparin Polysaccharide I, MW 5000 Da
 Catalog No. GT8082: Size = 1 mg/vial; Price = $325.00

Heparin Polysaccharide II, MW 7000 Da
 Catalog No. GT8083: Size = 1 mg/vial; Price = $285.00

Heparin Polysaccharide III, MW 9000 Da
 Catalog No. GT8084: Size = 1 mg/vial; Price = $285.00

Heparin Polysaccharide IV, MW 12000 Da
 Catalog No. GT8085: Size = 2 mg/vial; Price = $285.00

Heparin Polysaccharide VI, MW 15000 Da
 Catalog No. GT8086: Size = 2 mg/vial; Price = $250.00

Heparin Polysaccharide VII, MW 20000 Da
 Catalog No. GT8087: Size = 2 mg/vial; Price = $285.00

Glycosaminoglycans
Heparan Sulfate and
Heparan Sulfate Oligosaccharide :
 Heparan sulfate is a sulfate polysaccharide and structurally similar to heparin.   Two heparan sulfate oligosaccharides are offered as either Heparan Sulfate NS-Oligosaccharide (so-called N-sulfate-glucosamine-rich oligosaccharide blocks), or Heparan Sulfate NAc-Oligosaccharide (so-called N-acetyl-glucosamine-rich oligosaccharide blocks).

Heparan Sulfate
 Catalog No. GT9010: Size = 1 mg/vial; Price = $150.00

Heparan Sulfate NS-Oligosaccharide
 Catalog No. GT9011: Size = 1 mg/vial; Price = $368.00

Heparan Sulfate NAc-Oligosaccharide
 Catalog No. GT9012: Size = 1 mg/vial; Price = $285.00

Over Sulfated Glycosaminoglycan :
 Over sulfated glycosaminoglycan is a group of derivatives made by over O-sulfation of either heparan sulfate, dermatan sulfate or chondroitin sulfate.

Over Sulfated Heparan Sulfate
 Catalog No. GT9013: Size = 1 mg/vial; Price = $355.00

Over Sulfated Dermatan Sulfate
 Catalog No. GT9111: Size = 2 mg/vial; Price = $228.00

Over Sulfated Chondroitin Sulfate
 Catalog No. GT9121: Size = 2 mg/vial; Price = $168.00

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